Matsui WH. Curr Opin Drug Dis Dev. Bulbine bulbosa, Australia) especially to livestock, although the tubers of this and other species are roasted and eaten by bushmen. 2005;7:509–21. 2011;26:460–7. The juice of Bulbine annua, B. lagopus is said to have antibacterial and antifungal properties when applied externally. Annu Rep Comput Chem. ... Fenugreek seeds protect the liver from alcohol toxicity. 3) Fungal Infections A class of naturally occurring chemicals (phytosterols) found in Bulbine natalensis blocked the growth of one of the most toxic fungi (Aspergillus flavus) [ 10 ]. This succulent perennial plant (ht 40 cm) grows in wide clumps with fleshy leaves and has dainty spires of yellow starry flowers mainly in spring but also at other times during the year. It is generally sold under the scientific name Bulbine frutescens, though some nurseries use the synonyms B. fruticosum or B. caulescens. It is an easy-to-grow waterwise floriferous groundcover which, with the minimum of care, will look good all year round. Afr J Tradit Complement Altern Med. Not logged in 2008;4:217–41. 1998;12:66–73. Bulbine frutescens L. (Willd) was the only plant mentioned in this family . pp 491-510 | These active ingedients are contained in a pharmaceutically acceptable cream. 2011;51:2778–86. © 2020 Springer Nature Switzerland AG. It looks effective with blue flowers in spring, or lime-coloured leaves. Bulbine is also an ingredient in the first-aid herbal wound cream made during the practical session. 2004;13:1605–12. 2009;1:4–18. Unfortunately, the Amaryllis contains toxic substances like lycorine that is poisonous to cats if eaten. LigPlot+: multiple ligand–protein interaction diagrams for drug discovery. Bulbine frutescens. In conclusion, Palmidin C, AC1NSTKE and Bulbine-knipholone are the novel potent anticancer phytochemicals and need to be studied further in vitro and in vivo. The linear leaves have a jelly-like juice that can apparently be used for burns, rashes, cracked skin and other dermatological ailments. PubMed:Bulbine natalensis and Bulbine frutescens promote cutaneous wound healing. The root, leaf, and stem are used as medicine. Anticancer and mode of action of various phytochemicals present in the plant not yet has been studied. For the first time Palmidin C, AC1NSTKE, Bulbine-knipholone and 4′-Demethylknipholone 2′-β-D-glucopyranoside compounds have been reported for their anticancer potential. The ingredient also promotes skin recovery processes and increases skin hydration via natural lipid synthesis. 2017;51:1089–103. It needs frost protection. Deregulated signaling pathways/processes result in uncontrolled cell proliferation and cell survival. Bulbine … 2005;28:249. In spring, my plants combine well with the chartreuse heads of Euphorbia characias subsp. Discovery of natural product anticancer agents from biodiverse organisms. Bulbine is a very important plant from Tender Perennial. Wu T, Chen C, Li F, Chen Z, Xu Y, Xiao B, Tao Z. PLoS One. Over 10 million scientific documents at your fingertips. Open babel: an open chemical toolbox. Bulbine frutescens is a traditional medicinal plant of South Africa, has been preliminarily reported for anti-proliferative and anti-drug resistance property in cancer cells. Knipholone from. The effect of isofuranonaphthoquinone isolated from Bulbine frutescens on Jurkat T cells was determined. In conclusion, our study shows that the isofuranonaphthoquinone isolated from Bulbine frutescens possesses antiproliferative effects on Jurkat T cells. Phytoresources as potential therapeutic agents for cancer treatment and prevention. The effect was comparable to the anticancer agent BCNU. 20.1.4.2.2. 2006;35:301–3. Induction of phase I, II and III drug metabolism/transport by xenobiotics. PPK and SK acknowledges financial support from UGC, India and Central University of Punjab Bathinda, Punjab, India for providing financial assistance in the form of UGC-CSIR Senior Research Fellowship and UGC-BSR Research Start-Up-Grant, [No.F.30-372/2017(BSR)] respectively. The present in silico study was designed to assess the potential B. frutescens phytochemicals as novel natural inhibitors of signaling proteins involved in cancer. Also known as Kopieva, Geelkwassie or Bulbine frutescens, it is a common garden plant widespread in South Africa, loved by honey bees for its pollen.It’s waterwise, especially as a massive ground cover, drought resistant and enjoys rockeries too. Flavonoids are an important class of phytochemical. Int J Oncol. 2003. p. 418–20. J Cheminform. It is a most obliging plant in the garden, growing in sun or part-shade. 2003;66:1475–83. 2011;3:33. It gets about a 1′ tall and spreads to about 2 feet. Berman H, Henrick K, Nakamura H, Markley JL. Hey AM, just happened to be researching and combing through the web looking up different test boosters and supplements containing some of these compounds touted at being big time natural test boosters and well reading several reviews/studies on one in particular by the name of bulbine … The incisional wounds were used to test tensile strength of the healed wounds using a tensiometer.In the in vitro studies, neither extract caused cytotoxicity to either the fibroblast or keratinocyte cells. In my experience, it multiplies rapidly. A biochemical comparison of the in vivo effects of. This service is more advanced with JavaScript available, Phytochemistry: An in-silico and in-vitro Update J Comput Chem. The contact medium comprises an expressed gel from the plant Bulbine frutescens and may contain asiaticoside and panthenol. Duvoix A, Morceau F, Delhalle S, Schmitz M, Schnekenburger M, Galteau MM, Dicato M, Diederich M. 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